Apex body ICMR (Indian Council of Medical Research) in collaboration with the Hyderabad based biopharmaceutical company Biological E ltd has developed “Purified Antisera”. It has been prepared by injecting inactivated SARS-CoV2 in horses which can be used as a prophylaxis and could be a potential treatment for COVID-19.

Key Points

  • ICMR therapy is similar to the existing plasma therapy. But the only difference is in the Purified Antisera plasma is obtained from animals.
  • In this Purified Antisera therapy, antisera serum which is a blood-based serum has been prepared by injecting inactivated SARS-CoV2 in horses.
  • Purified Antisera was found that the serum recovered from the viral infection and it has antibodies called Equine Antisera which can be used against the corona virus.
  • The Equine Antiserum was segregated by ICMR led Pune’s National Institute of Virology, which was invited by ICMR in June 2020.


Such antibodies have also been obtained earlier from animals and have been used to cure several viral infections including the Hepatitis B (liver infection), rabies, tetanus, diphtheria and botulism.


Antiserum is a blood serum that builds “passive immunity”  through blood donation as it is done in case of Plasma Therapy. These are blood serum which are high in antibodies against specific antigens and can be  injected in humans to help boost the immune system to fight against specific infections.

Passive Immunity

Passive is immunity that is induced with the help of ready-made antibodies in the human body. Passive Immunity also occurs naturally, when the antibodies from mother is transferred to the baby through placenta (organ that develops in your uterus during pregnancy). It is induced in persons when they cannot generate their own antibodies.

Purified Antisera a potential treatment for COVID-19 Purified Antisera a potential treatment for COVID-19 COVID-19: ICMR develops “Purified Antisera” as treatment