CSIR: Council of scientific and Industrial Research, Centre for cellular and Molecular Biology (CSIR-CCMB) and the institute of genomics and integrative Biology (CSIR-IGIB) recently conduct a study. The study was published in the scientific journal nucleic acids research. According to the study, percentage genetic variance is unique in Indian sequences as compared to that of global genomes. Research Centres study brings out the importance of India centric population genomic initiative to be conducted globally. This is because India is rich in Genetic diversity and also in population density.
- India is the 2nd most populous country in the world.
- It encompasses of 17 per cent of World Population.
- There are more than 1.3 billion (130 crore) people living in India top also India is rich in Genetic diversity.
- In spite of this India is highly underrepresented in global genome study.
In 2019, Council of scientific and Industrial Research began the IndiGen Programme. The IndiGen programme was launched to fill the gap of genome sequences from different populations in India. IndiGen programme successfully completed genome Sequencing of 1029 self-declared healthy Indian who were drawn from different regions of the country.
IndiGen programme will find solutions that are applicable in preventive and predictive medicated measures. Also, the IndiGen programme aims to conduct genome sequencing of thousands of individuals from diverse ethnic groups of India. This will enable genetic epidemiology. Also, it will help in developing Public Health Technological Applications (PHTA) based on Population genome data.
What is genome?
In the fields of molecular biology and genetics, A genome is a sequence of genes or DNA in a Cell.
First Genome Project
UK was the first country to launch a genome programme. It launched the Genomics England programme that aimed to sequence hundred thousand genomes of patients with rare diseases.
32% genetic variants are unique in Indian sequences 32% genetic variants are unique in Indian sequences